药学英语题库

100分？100刀都嫌少哈

Natural pharmaceutical chemistry purpose From developing the new drug developing in natural medicine (the structure including the guide compound polishes with make over , entire combining),this is that we study natural pharmaceutical chemistry major objective. The degree of difficulty the pure compound new drug is developed is big , the period is long , cost is high, the poisonous chemistry medicine side effect is big , easy to produce resistance to drugs, health brings about to the human body hurt, but the activity component sometimes has higher security from nature that green gets in life plant , medicine and medicine taking natural medicine as raw material extract thing favour accepting people gradually in all the countries in the world therefore. (1) is made by nature a great variety , structure are new and original , the hit rate that the pharmacology sifts is higher than composing compound , originate from natural guide compound having hope very much becoming the new drug curing difficult and complicated cases's , study direction therefore one already becoming a nowadays from the new drug developing in natural medicine is popular. Somebody forecasts , future natural medicine will have equal shares with chemistry medicine, power of assuming a situation of tripartite confrontation together with living things medicine.(2) A number of natural active compounds, because there are some defects, such as efficacy is not satisfactory, or side effects must exist, or because the content is too low, shortage of resources, it is difficult to Medium derived from natural raw materials, or because the structure was too complex, synthetic is also very difficult, so there is no direct the development and utilization of their own future. However, the natural active ingredients for the lead compounds, structural modification or structural Transformation, and eventually developed into new drugs. For example: synthetic morphine substitutes - is scheduled for piperaquine (meperidine), morphine is retained in the structural parts of an effective (analgesic effect of the same!), And its addictive than morphine decreased. Another example: the active ingredient in coca leaves cocaine has a very strong narcotic effect, but toxic, easy to addiction, through research design and synthesis of local anesthetics such as procaine. Again Example: to extract from the Artemisia annua with the separation of anti-malarial activity of artemisinin, is a heat-labile compounds, such as its hydrogenated, methylated derivatives artemether made after the markedly improved stability, anti - more enhanced malaria activity.

Natural pharmaceutical chemistry purpose From developing the new drug developing in natural medicine (the structure including the guide compound polishes with make over , entire combining),this is that we study natural pharmaceutical chemistry major objective. The degree of difficulty the pure compound new drug is developed is big , the period is long , cost is high, the poisonous chemistry medicine side effect is big , easy to produce resistance to drugs, health brings about to the human body hurt, but the activity component sometimes has higher security from nature that green gets in life plant , medicine and medicine taking natural medicine as raw material extract thing favour accepting people gradually in all the countries in the world therefore.(1) is made by nature a great variety , structure are new and original , the hit rate that the pharmacology sifts is higher than composing compound , originate from natural guide compound having hope very much becoming the new drug curing difficult and complicated cases's , study direction therefore one already becoming a nowadays from the new drug developing in natural medicine is popular. Somebody forecasts , future natural medicine will have equal shares with chemistry medicine, power of assuming a situation of tripartite confrontation together with living things medicine. (2) is not the natural activity compound short, because of existence some defects, existence definitely poisons or a side effect, or resource shortage, is difficult to draw materials from natural raw material middle because contents are very low,or excessively, complicated , compose because of structure if pesticide effect is not ideal, also very difficult , develop the future making use of therefore self is not direct. And but take natural activity component as guide compound, the structure being in progress polishes or structure reforms, ultimate exploitation becomes a new drug.For example: The cries of a baby replaces the morphine combining substitution- stablely (dolantin) , (the effect is invariable now that effective in having reserved morphine structure part eases pain)! ,Use whose more obvious than morphine habituation sex lessening. Such as: In Gukeye, active constituent cocain has the very strong anaesthesia effect, but big , easily able addiction of toxicity, by studying the ethocaine designing the anaesthetic having composed waits. No matter how regular: Active Artemisia apiacea is plain from the malaria extracting having parting for in Artemisia apiacea resisting , is one kind of hot unsteady compound, the stability improves obviously after manufacturing the Wormwood A ether derivative if hydrogenate with the person , methylate,resist malaria activity strengthening especially.

1 ：天然产品2 ：前言现代制药方法的分析3 ：开发新的药物（ 1 ） 第4开发新的药物（ 2 ） 5 ：药物滥用6 ：范围的药理学7 ： FDA的职责和活动8 ：寻找新的药物

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