对某人影响大英文

可以的。make a great influence on sb对某人有很大的影响eg.His speech made a great influence on me.他的演讲对我影响很大。不过习惯上，我们是用have a great influence on 比较多。

affect someone

这个词组这么用： His magnificent ideas had a great influence on me. 他崇高的思想对我有过巨大的影响。Conclusion Acute craniocerebral trauma could make a great influence on the thyroid function in early stage.结论急性颅脑损伤早期甲状腺功能有明显异常. make a difference :有关系，有影响，有重要性make no difference：没有关系，没有重要性如：It won't make much difference whether you go today or tomorrow.你今天去或明天去没有多大关系.Does that make any difference，Is it important,need we consider it?那是否有重要性？我们是否需要考虑它?